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Islet Sheet Goes Global

June 13th, 2013

A year ago our only collaborator was Jonathan Lakey at UCI. This has changed a lot recently.

Thanks to growing interest in the need for encapsulation to protect islets made from human stem cells, and through contacts made through the JDRF/Helmsley Encapsulation Consortium, the number of collaborators for Islet Sheet research has gone up 500% in the last three months. The Islet Sheet is increasingly recognized as the most promising approach to islet encapsulation.

Jonathan Lakey continues to be our main collaborator in animal studies. He will be publishing STZ (Streptozotocin) pig studies of Islet Sheets at the IPITA meeting in September 2013. The International Pancreas and Islet Transplantation Association is the primary conference of scientists and companies working to cure autoimmune (type 1) diabetes with islet transplantation, including encapsulated islet implantation. Dr. Lakey’s work has been tapped for three oral presentations.

With Richard Bergman’s group at Cedars-Sinai, we are planning metabolic studies with pancreatectomized dogs. We are in discussions with several other academic groups funded by JDRF.

We are also working with private companies, including a major ESC (embryonic stem cell) islet company.

In twenty years of Islet Sheet research there has never been more interest in our technology. Our goal is to collaborate with everyone who has a source of insulin-producing cells.

 

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2 Responses to “Islet Sheet Goes Global”

  1. Scott – great to see this update! Congrats to you and the team on all the successes this past year.

  2. Brian says:

    I am glad to hear encapsulation approach to a practical “cure for diabetes” is beginning to get more notice as from my perspective, encapsulation is more of a technology challenge. I say this because the two barriers to this working is protecting the beta cells from immune attack and letting nutrients in to nourish the cells and finding a source of beta cells. Personally I think this is a better approach then the AP.

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