Categories
- A Cure for Diabetes? (2)
- Clinical Practice (3)
- Conference Report (2)
- Current Research (30)
- Diabetes in Popular Culture (2)
- Diabetes in the Press (6)
- Diabetes Technology (3)
- Diatribe (1)
- Guest Essays (4)
- Islet Sheet Updates (13)
- Letters (2)
- Press Release (1)
- Scott's Opinion (22)
- The Marat/King Dialogues (8)
- Type 1 Diabetes Classic (5)
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Author Archive
Islet Sheet Goes Global
June 13th, 2013
A year ago our only collaborator was Jonathan Lakey at UCI. This has changed a lot recently. Thanks to growing interest in the need for encapsulation to protect islets made from human stem cells, and through contacts made through the JDRF/Helmsley Encapsulation Consortium, the number of collaborators for Islet Sheet research has gone up 500% [...]
Cure for Diabetes 2013: Cost of the Crucial Experiment
June 8th, 2013
We are ready for the crucial animal study to push the Islet Sheet into clinical trials. The definitive model is the pancreatectomized dog, which is reliably diabetic, well-understood, and will accurately predict the safety and efficacy of the Islet Sheet in humans with type 1 diabetes. In the discussion of my previous post, I was [...]
Research Update and 2013 Experimental Plan
May 22nd, 2013
Islet Sheet Research Background Hanuman Medical Foundation has been funding the Islet Sheet Project with the requirement that we move into the clinic as fast as possible. We restarted the project in 2009 with a plan to perfect the Islet Sheet in laboratory and rodent studies, then move on to the definitive large-animal model of [...]
Islet Sheet Project Update
May 16th, 2013
It’s been months since I took family leave from writing The Sheet. I have much to report on the Islet Sheet Project. For the balance of 2013 we will engage in some focused, small-scale studies to address problems identified in the pig studies. More on that very soon. Here are some other developments that I’ll [...]
A Cure for Diabetes?
April 30th, 2013
I often get e-mails from readers who have read of some newly published research and wonder if it means that we have a cure for type I diabetes. Such announcements seem to come more or less every month. So I have decided to inaugurate a regular feature in The Sheet to inquire into these announcements. [...]
Brief Update from Scott
April 8th, 2013
My family leave continues but will be over in a few weeks. I appreciate your patience. There have been many developments on the Islet Sheet Project, which I look forward to telling you about. The VoxPop people have secured funding for their documentary on finding a cure for diabetes, and have changed the film’s working [...]
Welcome Guest Blogger Will Hall
January 30th, 2013
Ed: While Scott King remains absent on family matters, we’re very pleased to introduce Will Hall, a higher education development officer who has lived with type 1 diabetes for 25 years, and who has volunteered to share his personal experience in occasional guest postings. The Hanuman website and this blog tend to be dominated by [...]
A Brief Pause for The Sheet
December 10th, 2012
From the editor of The Sheet, for Hanuman Medical Foundation: For urgent family reasons, Scott King will take a break from writing his twice-monthly blog posts. Scott’s sister was suddenly diagnosed with inoperable brain cancer and needs the support of her entire family for a while. Fortunately, the large-mammal experiments with the Islet Sheet can [...]
Signal Breakthrough: Islet Sheets Thrive in Pigs
November 26th, 2012
At the Islet Sheet Project we have entered a new era — the era of large-animal efficacy results. This is the most important and perilous step on the path from thin-sheet concept to clinical product. Experiments are expensive, and a few failures could mean the end of the project. I am happy to report a [...]
Support for Encapsulation Is Growing
November 12th, 2012
As regular readers know, I believe that the best prospects for a near-term practical cure for type 1 depend on islet encapsulation technology. And I see this approach winning more and more support. The latest evidence that support is growing for encapsulation is a new grant by the California Institute for Regenerative Medicine (CIRM) to [...]
