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Archive for the ‘Islet Sheet Updates’ Category
Research Update and 2013 Experimental Plan
May 22nd, 2013
Islet Sheet Research Background Hanuman Medical Foundation has been funding the Islet Sheet Project with the requirement that we move into the clinic as fast as possible. We restarted the project in 2009 with a plan to perfect the Islet Sheet in laboratory and rodent studies, then move on to the definitive large-animal model of [...]
Islet Sheet Project Update
May 16th, 2013
It’s been months since I took family leave from writing The Sheet. I have much to report on the Islet Sheet Project. For the balance of 2013 we will engage in some focused, small-scale studies to address problems identified in the pig studies. More on that very soon. Here are some other developments that I’ll [...]
Hanuman Collaborator Wins JDRF Grant to Study Encapsulation
May 10th, 2013
by John D. Golenski Executive Director, Hanuman Medical Foundation I have good and bad news to share with readers of The Sheet. First the bad: Scott King’s sister, Debby King Mustard, who was diagnosed last December with inoperable brain cancer, passed away peacefully Sunday morning. Scott and other family members were with her. The [...]
Signal Breakthrough: Islet Sheets Thrive in Pigs
November 26th, 2012
At the Islet Sheet Project we have entered a new era — the era of large-animal efficacy results. This is the most important and perilous step on the path from thin-sheet concept to clinical product. Experiments are expensive, and a few failures could mean the end of the project. I am happy to report a [...]
Islet Sheet Presentation at EASD in Berlin
October 2nd, 2012
Today, at the annual Meeting of the European Association for the Study of Diabetes (EASD), Prof. Jonathan Lakey presented the first data from the ongoing UC Irvine – Islet Sheet Medical study of the Islet Sheet using diabetic pigs . To view the poster click here. The beautiful photograph (lower left) of the Islet Sheet, fabricated [...]
Designing a Definitive Islet Sheet Study
April 2nd, 2012
Large-animal studies will demonstrate whether the Islet Sheet is ready for a clinical trial. In previous posts I have discussed the partnership doing this study: the Cedars-Sinai Diabetes and Obesity Research Institute, the islet transplantation group at UC Irvine, and our company Islet Sheet Medical. I have also laid out the study design. Today I want to describe [...]
The Crucial Year for Islet Sheet is 2012
January 17th, 2012
A year ago I posted an article to this blog titled “The Crucial Year for Islet Sheet is 2011.” I was off by a year, as it turned out; last year was a transition year. The crucial year begins today. As I wrote last year, “The definitive experimental model is large animals (pig, dog, monkey) [...]
The Year of the Dog
November 27th, 2011
Welcome to our new website! It is a pleasure to resume this blog, now named The Sheet—for the Islet Sheet, of course. (It’s also journalism slang for a periodical.) This is an exciting time at Islet Sheet Medical. We have made an important addition to our team. VoxPop Films is making a documentary about our [...]
Function and Viability of Human Islets Encapsulated in Alginate Sheets: The Poster
June 19th, 2011
Soon I am off to the ADA meeting in San Diego that starts Friday. So I’ll give you a report on what the diabetes clinicians know after the conference. So this week a little supplement on the IPITA conference in Prague (see previous post). Some people let me know they want to see the poster [...]
IPITA 2011: Islet Researchers in Prague
June 6th, 2011
As promised, here is my report from the 2011 meeting of the International Pancreas and Islet Transplant Association meeting in Prague. The highlight for the Islet Project team was unveiling some significant results in the poster to the right, “Function and viability of human islets encapsulated in alginate sheets: in vitro and in vivo culture.” [...]
